Dianne N. Irving
copyright December 20, 2020
Reproduced with Permission
Are there scientific concerns re FDA's VRBPAC report on m-RNA vaccines?
This a short but precise concern about some of the science used by our FDA in its report on genetically engineered m-RNA vaccines [posted at: https://www.fda.gov/media/144452/download]. While normal genetic changes in genes involved in "therapies" aren't a problem (given that obvious scientific criteria are met!), those genetic changes are not passed down through future generations. However, when genetic changes in germ line cells (sperm and oocytes ("eggs') are involved, such genetic changes are passed down through all of one's future generations. Hopefully the FDA will reconsider their science on at least 4 critical points.
*1. The report defines "human genome" as consisting of ONLY the DNA in the nucleus.
But can that be accurate? As documented in human genetic textbooks and websites for years, the scientific definition of the "human genome" includes ALL of the DNA in a human cell -- BOTH the DNA in the cell nucleus AND the DNA in the mitochondria floating around outside the nucleus in the cell's cytoplasm. So it would seem that because m-RNA changes the functioning of a piece of the DNA in the mitochondria it THUS DOES change the "human genome". See, e.g.: [emphases mine]
- -- Tom Strachan and Andrew P. Read, Human Molecular Genetics 2 (2nd ed.) (New York: John Wiley & Sons, Inc., 1999):
- -- In animal cells, DNA is found in both the nucleus and the mitochondria. (p. 10)
- -- The mitochondria also have ribosomes and a limited capacity for protein synthesis. (p. 18)
- -- The human genome is the term used to describe the total genetic information DNA content) in human cells. It really comprises two genomes: a complex nuclear genome which accounts for 99.999d% of the total genetic information, and a simple mitochondrial genome which accounts for the remaining 0.0005%. ... Mitochondria possess their own ribosomes and the few polypeptide-encoding genes in the mitochondrial genome produce mRMAs which are translated on the mitochondrial ribosomes. (p. 139)
- -- Benjamin Lewin, Genes VII (New York: Oxford University Press, 2000):
- -- A genome consists of the entire set of chromosomes for any particular organism , and therefore comprises a series of DNA molecules, each of which contains a series of many genes. The ultimate definition of a genome is to determine the sequence of the DNA of each chromosome. (p. 4)
- -- Genes not residing within the nucleus are generally described as extranuclear ; they are transcribed and translated in the same organelle compartment ( mitochondrion or chloroplast ) in which they reside. By contrast, nuclear genes are expressed by means of cytoplasmic protein synthesis. ... One type of uniparental inheritance is seen in higher animals. Maternal inheritance can be predicted by supposing that the mitochondria are contributed entirely by the ovum and not at all by the sperm. So the mitochondrial genes are derived exclusively from the mother; and in males they are discarded each generation. (p. 81)
- -- DNA , or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person's body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA ). https://medlineplus.gov/genetics/understanding/basics/dna/
- -- The human genome is a complete set of nucleic acid sequences for humans, encoded as DNA within the 23 chromosome pairs in cell nuclei and in a small DNA molecule found within individual mitochondria. https://en.wikipedia.org/wiki/Human_genome
- -- Although most DNA is packaged in chromosomes within the nucleus, mitochondria also have a small amount of their own DNA (called mitochondrial DNA or mtDNA ). https://medlineplus.gov/genetics/gene/tymp/
- -- Although most DNA is packaged in chromosomes within the cell nucleus, cell structures called mitochondria also have a small amount of their own DNA (known as mitochondrial DNA). https://medlineplus.gov/genetics/understanding/dtcgenetictesting/ancestrytesting/
*2. The report states that this "foreign" m-RNA is destroyed after it finishes editing the gene, not to worry.
However, perhaps the mRNA is destroyed, but the editing of the gene in the mitochondria is not ; it is permanent.
*3. The report also claims that the vaccine delivers m-RNA only to specific immune cells at the injection site.
But is that what really happens? As Dr. Bhakdi (and many other scientific experts) have warned, "Once a gene-based vaccination is injected in your arm, within minutes the vaccine (mRNA) spreads throughout your body ." [See, https://rairfoundation.com/dire-warning-prominent-virologist-dr-sucharit-bhakdi-exposes-major-risks-of-gene-altering-vaccine-video/ ]
*4. Finally, the report states that the changes that m-RNA's make to one's genes are not passed down through future generations.
Yet how about the latest comments by world renown virologist Dr. Bhakdi when he explains that when the vaccine is injected, it causes mRNA to spread throughout body, and that would include one's germ line cells (sperm and oocytes ("eggs") ? [See: "Dire Warning: Prominent Virologist Dr. Sucharit Bhakdi Exposes 'Major Risks' of Gene-Altering Vaccine (Video)", at: https://rairfoundation.com/dire-warning-prominent-virologist-dr-sucharit-bhakdi-exposes-major-risks-of-gene-altering-vaccine-video /] Thus wouldn't the genetic changes be passed down through all future generations every time fertilization takes place? As the Center for Genetics and Society (not a "prolife" organization!) has extensively critically documented scientifically for years, the "editing" of germ line cell genes IS passed down through future generations. See, e.g.:
Conclusion:
Given such concerns, hopefully the FDA will look into them. Human lives are at stake.
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